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About us

OUR MISSION

Revolutionizing autoimmune
disease treatment with
innovative biologics

Signal26 Biotherapeutics is dedicated to developing a groundbreaking biologic treatment for Psoriasis. Through our partnership with a leading research university in Switzerland, we have identified the interleukin 26 (IL-26) signalling pathway as a novel target. With our novel anti-IL-26 antibody, we aim to revolutionize the treatment of autoimmune diseases.

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Based on active research supported by leading institutions and partners

WHAT WE DO

Revolutionizing the treatment of autoimmune disorders, one signal at a time

Demonstrated Efficacy

Signal26 Biotherapeutics is a Biotechnology startup dedicated to advancing the development of a novel biological drug for the treatment of Pustular Psoriasis. In collaboration with our colleagues at CHUV, we are pioneering research into the role of interleukin 26 (IL-26) in
autoimmune disorders.

Roadmap

Our team

INNOVATION

Our team

Meet the experienced team behind Signal26 Biotherapeutics

HEAD OF R&D

Dr. Lefteris Zacharia, PhD

Dr. Zacharia is an associate professor of Pharmacology at the University of Nicosia who has been leading the anti-IL-26 project since 2021 as part of AVVA Pharmaceuticals LTD.

ACCOUNTING & ADMINISTRATION SPECIALIST

Ueli Ambauen

Mr. Ambauen has extensive experience in finance and accounting in Switzerland. At Signal26 Biotherapeutics, he has been responsible for accounting and administration.

Research Associate

Yu-Noël Larpin, PhD

Dr. Yu-Noël Larpin earned his PhD in Cell Biology from the University of Bern. With expertise in molecular biology, biophysics, and entrepreneurial leadership, he combines scientific discovery with innovation to advance therapies for autoinflammatory diseases.

Senior Biotechnologist

Mylène Talabardon, PhD

Dr. Talabardon earned her PhD in Biotechnology from The Ohio State University. With over 20 years of experience, she has led pharmaceutical teams in process development, validation, and regulatory strategy, shaping global approaches to biologics manufacturing.

BIOTECHNOLOGY ENGINEER

Sergey Tolmachev

Mr. Tolmachev has extensive experience in R&D management of new drugs at all stages, including small molecules, biological products, APIs, and medical devices. He has expertise in B&D, strategic and operational marketing, biotechnological production, and establishing quality management systems (ISO, GMP).

Chairwoman

Daria Dikovskaya, MSc

Ms. Dikovskaya dedicated 4 years to Biomedical research at Imperial College London and UCL before pursuing entrepreneurship in the biotech. space. Currently, she is an MBA candidate specialising in business for social and environmental impact.

A scientist wearing blue gloves using a multichannel pipette to transfer liquid into a well plate in a laboratory setting.

OUR TEAM

We are a team of experts
dedicated to bringing relief to
thousands of patients.

Signal26 Biotherapeutics is dedicated to advancing the global understanding of autoinflammation mechanisms and their contribution to Psoriasis, Inflammatory Bowel Disease, and Rheumatoid Arthritis. Through our partnership with a leading research university in Switzerland, we have identified the interleukin 26 (IL-26) signalling pathway as a novel target.

Our novel anti-IL-26 antibody has shown promising results in blocking the aberrant function of IL-26 in murine models. We are committed to swiftly advancing this innovative therapy to clinical trials.

A scientist wearing yellow safety goggles examining an orange liquid in a round-bottom flask, illuminated by bright light.

Interested in joining the team?

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About us

Revolutionizing autoimmune
disease treatment with
innovative biologics